Cytotec

By A. Vibald. Southern Illinois University at Carbondale.

Two patients in the comparator group had both a new infecting organism and a superinfecting organism (12001 and 105002) purchase 200 mcg cytotec overnight delivery medications side effects. These patients were classified as having a superinfection by the applicant and are not included in the 12 patients with superinfections in the comparator group (Table 18F). Classified by the applicant as a superinfection The bacteriological eradication rates for all isolated organisms (excluding indeterminate and missing responses) are shown in Table 19. Although the subanalyses below present interesting results, it is difficult to make conclusions from the data due to the number of inter-related variables. For more information on individual patients with persistence, superinfection, or new infection, see Tables 18A through 18F above. When analyzed by country of enrollment, eradication rates* were slightly lower than the overall rates in Mexico (75% [27/36] ciprofloxacin versus 81% [30/37] comparator) and Costa Rica (77% for both treatment groups [13/17] and [10/13]). Eradication rates were higher than the overall rates in Peru (90% [56/62] ciprofloxacin versus 93% [64/69] comparator). There was a larger difference between treatment group eradication rates in the United States (86% [19/22] ciprofloxacin versus 45% [13/29] comparator) than in the overall rates. This was due to the ciprofloxacin arm having no superinfections or new infections and the comparator arm having 6 superinfections and 3 new infections. There was also a larger difference between treatment group eradication rates* in Caucasians (86% [68/79] ciprofloxacin versus 67% [58/87] comparator) than in the overall rates. The eradication rates were lower for both treatment groups in Hispanics (75% [49/65] ciprofloxacin versus 77% [53/69] comparator) when compared to the overall rate, and higher for both treatment groups in the uncoded race subgroup (92% [60/65] ciprofloxacin versus 93% [68/73] comparator). In males, the comparator eradication rate was 79% [26/33], compared to 88% [28/32] in the ciprofloxacin group. Comparator drug performed worse than ciprofloxacin in all age groups except ≥ 2 years to < 6 years group (87% [65/75] versus 85% [70/82]. In the ≥ 12 month to <24 month age group, the comparator group had eradication rate of 83% [20/24] versus 92% [24/26] for the ciprofloxacin group. In the ≥ 6 years to <12 years group, the comparator had an eradication rate of 77% [85/111] versus 84% [77/92] for the ciprofloxacin group. In the ≥12 years, < 17 years the comparator had an eradication rate of 52% [11/21] versus 64% [7/11] for the ciprofloxacin group.

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